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Long-term humoral immune response in persons with asymptomatic or mild SARS-CoV-2 infection, Vietnam
Emerging Infectious Diseases Số 2, năm 2021 (Tập 27, trang 663-666)
ISSN: 10806040
ISSN: 10806040
DOI: 10.3201/eid2702.204226
Tài liệu thuộc danh mục:
Article
English
Từ khóa: Adolescent; Adult; Antibodies, Viral; Asymptomatic Infections; Child; COVID-19; Female; Humans; Immunity, Humoral; Longitudinal Studies; Male; Middle Aged; Nucleocapsid Proteins; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Time Factors; Vietnam; Young Adult; neutralizing antibody; coronavirus spike glycoprotein; nucleocapsid protein; virus antibody; adolescent; adult; antibody response; antibody titer; Article; blood sampling; child; clinical article; coronavirus disease 2019; disease surveillance; enzyme linked immunosorbent assay; female; follow up; hospitalization; human; humoral immunity; immune response; inoculation; male; oxygen supply; polymerase chain reaction; protein targeting; SARS coronavirus; serology; seroprevalence; upper respiratory tract; vaccination; Viet Nam; viral clearance; virus neutralization; virus nucleocapsid; virus replication; asymptomatic infection; blood; immunology; longitudinal study; middle aged; time factor; Viet Nam; virology; young adult
Tóm tắt tiếng anh
Antibody response against nucleocapsid and spike proteins of SARS-CoV-2 in 11 persons with mild or asymptomatic infection rapidly increased after infection. At weeks 18-30 after diagnosis, all remained seropositive but spike protein-targeting antibody titers declined. These data may be useful for vaccine development. � 2021 Centers for Disease Control and Prevention (CDC). All rights reserved.
