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Mild versus severe COVID-19: Laboratory markers
International Journal of Infectious Diseases Số , năm 2020 (Tập 95, trang 304-307)
DOI: 10.1016/j.ijid.2020.04.061
Tài liệu thuộc danh mục: ISI, Scopus
English
English
Từ khóa: alanine aminotransferase; albumin; amino terminal pro brain natriuretic peptide; antithrombin; aspartate aminotransferase; C reactive protein; CXCL3 chemokine; D dimer; ferritin; fibrin degradation product; fibrinogen; gamma interferon inducible protein 10; glucose; granulocyte colony stimulating factor; interleukin 1; interleukin 10; interleukin 2; interleukin 2 receptor; interleukin 6; interleukin 7; interleukin 8; lactate dehydrogenase; monocyte chemotactic protein 1; procalcitonin; troponin; tumor necrosis factor; biological marker; activated partial thromboplastin time; CD8 lymphocyte count; comorbidity; comparative study; coronavirus disease 2019; creatinine blood level; disease course; disease marker; disease severity assessment; eosinophil count; hospital patient; human; intensive care unit; laboratory test; leukocyte count; lymphocyte count; neutrophil count; oxygen saturation; platelet count; predictive value; protein blood level; prothrombin time; risk assessment; Short Survey; thrombin time; Betacoronavirus; blood; Coronavirus infection; pandemic; virus pneumonia; Betacoronavirus; Biomarkers; Coronavirus Infections; Humans; Intensive Care Units; Pandemics; Pneumonia, Viral
Tóm tắt tiếng anh
The number of COVID-19 patients is dramatically increasing worldwide. Treatment in intensive care units (ICU) has become a major challenge; therefore, early recognition of severe forms is absolutely essential for timely triaging of patients. While the clinical status, in particular peripheral oxygen saturation (SpO2) levels, and concurrent comorbidities of COVID-19 patients largely determine the need for their admittance to ICUs, several laboratory parameters may facilitate the assessment of disease severity. Clinicians should consider low lymphocyte count as well as the serum levels of CRP, D-dimers, ferritin, cardiac troponin and IL-6, which may be used in risk stratification to predict severe and fatal COVID-19 in hospitalised patients. It is more likely that the course of the disease will be unfavourable if some or all of these parameters are altered. � 2020 The Author(s)
