Trang chủ    Giới thiệu    Danh mục công bố    Thống kê công bố    Liên hệ   
Trang chủ Công bố quốc tế • Giới thiệu     • Tài liệu hướng dẫn
  • Chỉ mục bởi
  • Năm xuất bản
LIÊN KẾT WEBSITE

Mesoporous silica (SBA-15) with enriched amidoxime functionalities for pH-controlled anticancer drug delivery

Ulagesan Division of Fisheries Life Sciences, Pukyong National University, Nam-gu, Busan, 48513, South Korea|
Youn-Hee (55891974700) | Taek-Jeong (57700475400); Choi | Seong-Cheol (57277834400); Nam | Kokila (57345221600); Kim Institute of Fisheries Sciences, Pukyong National University, Gijang-gun, Busan, 46041, South Korea| Krishnapandi (57218625860); Thirupathi Department of Physics, Sri Moogambigai College of Arts and Science for Women, Palacode, 636808, India| Thi (57544735600); Alagumalai Faculty of Environmental and Chemical Engineering, Duy Tan University, 03 Quang Trung, Hai Chau, Danang, 550000, Viet Nam| Madhappan (57225097664); Tuong Vy Phan Center for Advanced Chemistry, Institute of Research and Development, Duy Tan University, 03 Quang Trung, Hai Chau, Danang, 550000, Viet Nam| Selvakumari (57191597379); Santhamoorthy School of Chemical Engineering, Yeungnam University, Gyeongsan, 38544, South Korea|

Inorganic Chemistry Communications Số , năm 2022 (Tập 146, trang -)

ISSN: 13877003

ISSN: 13877003

DOI:

Tài liệu thuộc danh mục:

Article

English

Tóm tắt tiếng anh
Amidoxime (AMI) functionalized mesoporous silica material (SBA-15@AMI NPs) was synthesized by surface modification approaches. This method allows for the creation of a higher concentration of amidoxime ligand groups to the SBA-15′s surface without affecting the morphology. The synthesized SBA-15@AMI NPs were verified using a range of instrumental characterizations. Further, the drug loading and pH-responsive release behavior of the SBA-15@AMI NPs were examined using Dox as model anticancer drug. The biocompatibility and cellular uptake behavior was studied using MCF-7 cell line. Overall, the prepared SBA-15@AMI NPs could be applied as pH-responsive drug delivery applications in cancer therapy. © 2022 Elsevier B.V.

Xem chi tiết