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Viral respiratory tract infections among patients with acute undifferentiated fever in Vietnam
Southeast Asian Journal of Tropical Medicine and Public Health Số 5, năm 2010 (Tập 41, trang 1116-1126)
ISSN: 1251562
ISSN: 1251562
DOI:
Tài liệu thuộc danh mục: Scopus
Article
English
Từ khóa: immunoglobulin A; immunoglobulin G; immunoglobulin M; acute disease; article; chi square distribution; differential diagnosis; enzyme linked immunosorbent assay; epidemiology; fever; human; respiratory tract infection; Viet Nam; virology; Acute Disease; Chi-Square Distribution; Diagnosis, Differential; Enzyme-Linked Immunosorbent Assay; Fever; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Respiratory Tract Infections; Seroepidemiologic Studies; Vietnam
Tóm tắt tiếng anh
To investigate the proportion of viral respiratory tract infections among acute undifferentiated fevers (AUFs) at primary health facilities in southern Vietnam during 2001-2005, patients with AUF not caused by malaria were enrolled at twelve primary health facilities and a clinic for malaria control program. Serum was collected on first presentation (t0) and after 3 weeks (t3) for serology. After exclusion of acute dengue infection, acute and convalescent serum samples from 606 patients were using enzyme-linked immunoassays to detect IgA, as well as IgM and IgG antibodies against common respiratory viruses. Paired sera showed the following infections: human parainfluenza virus (HPIV, 4.7%), influenza B virus (FLUBV, 2.2%), influenza A virus (FLUAV, 1.9%) and human respiratory syncytial virus (HRSV, 0.6%). There was no association between type of infection and age, sex or seasonality; some inter-annual differences were observed for influenza. Antibody prevalence, indicative of previous infections, was relatively low: HPV, 56.8%, FLUBV, 12.1%; FLUAV, 5.9% and HRSV, 6.8%.