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Development and Validation of a Scoring System to Predict Severe Acute Lower Gastrointestinal Bleeding in Vietnamese
Digestive Diseases and Sciences Số 3, năm 2021 (Tập 66, trang 823-831)
ISSN: 1632116
ISSN: 1632116
DOI: 10.1007/s10620-020-06253-y
Tài liệu thuộc danh mục:
Article
English
Từ khóa: Acute Disease; Aged; Area Under Curve; Asian Continental Ancestry Group; Blood Pressure; Female; Gastrointestinal Hemorrhage; Heart Rate; Hematocrit; Humans; Logistic Models; Lower Gastrointestinal Tract; Male; Middle Aged; Platelet Count; Predictive Value of Tests; Prospective Studies; Retrospective Studies; Risk Assessment; Risk Factors; ROC Curve; Severity of Illness Index; Symptom Assessment; Vietnam; acetylsalicylic acid; anticoagulant agent; antidiabetic agent; antihypertensive agent; bronchodilating agent; clopidogrel; corticosteroid; fresh frozen plasma; nonsteroid antiinflammatory agent; steroid; warfarin; abdominal pain; adult; Article; blood transfusion; chronic obstructive lung disease; cohort analysis; colitis; colon adenocarcinoma; colon ulcer; colonoscopy; diabetes mellitus; diarrhea; Dieulafoy disease; disease severity; diverticulosis; erythrocyte concentrate; erythrocyte transfusion; faintness; false aneurysm; female; fever; gastrointestinal hemorrhage; heart rate; hematocrit; hemorrhoid; hemorrhoidectomy; hospital patient; human; hypertension; inflammatory bowel disease; international normalized ratio; major clinical study; male; middle aged; multicenter study; platelet count; priority journal; prospective study; rectum hemorrhage; retrospective study; risk factor; scoring system; systolic blood pressure; tertiary care center; thrombocyte transfusion; Viet Nam; Vietnamese; acute disease; aged; area under the curve; Asian continental ancestry group; blood pressure; ethnology; gastrointestinal hemorrhage; lower gastrointestinal tract; predictive value; procedures; receiver operating characteristic; risk assessment; severity of illness index; statistical model; symptom assessment
Tóm tắt tiếng anh
Background/Aims: The prevalence of acute lower gastrointestinal bleeding (ALGIB) has progressively increased worldwide but there are few studies in Asian populations. This study aimed to develop and validate a scoring system to predict severe ALGIB in Vietnamese. Methods: Risk factors for severe ALGIB were identified by multiple logistic regression analysis using data from a retrospective cohort of 357 patients admitted to a tertiary hospital. These factors were weighted to develop the severe acute lower gastrointestinal bleeding (SALGIB) score to predict severe ALGIB. The performance of SALGIB was validated in a prospective cohort of 324 patients admitted to 6 other hospitals using area under the receiver operating characteristics curve (AUC) analysis. Results: There were four factors at admission independently associated with severe ALGIB in the derivation cohort: heart rate ≥ 100/min, systolic blood pressure < 100 mmHg, hematocrit < 35%, and platelets ≤ 150 × 103/µL. The SALGIB score determined severe ALGIB with AUC values of 0.91 and 0.86 in the derivation and validation cohorts, respectively. A SALGIB score < 2 associated with low risk of severe ALGIB in both cohorts (3.7% and 1.2%; respectively). Conclusions: The SALGIB score has good performance in discriminating risk of severe ALGIB in Vietnamese. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
