LIÊN KẾT WEBSITE
Endemic diphtheria in Ho Chi Minh City; Viet Nam: A matched case-control study to identify risk factors of incidence
Vaccine Số 51, năm 2010 (Tập 28, trang 8141-8146)
ISSN: 0264410X
ISSN: 0264410X
DOI: 10.1016/j.vaccine.2010.09.088
Tài liệu thuộc danh mục: Scopus
Article
English
Từ khóa: antibiotic agent; diphtheria pertussis tetanus vaccine; diphtheria tetanus vaccine; diphtheria toxoid; diphtheria vaccine; penicillin G; adolescent; antibiotic therapy; article; bath; case control study; child; controlled study; Corynebacterium diphtheriae; diphtheria; drug efficacy; edema; endemic disease; female; fever; frequency analysis; hoarseness; human; immunization; incidence; inoculation; kidney disease; laryngitis; major clinical study; male; myalgia; myocarditis; neck edema; personal hygiene; pharyngitis; preschool child; priority journal; risk factor; school child; skin care; skin defect; sore throat; Viet Nam; Adolescent; Case-Control Studies; Child; Child, Preschool; Cities; Diphtheria; Diphtheria Toxoid; Female; Humans; Incidence; Infant; Male; Risk Factors; Urban Population; Vaccination; Vietnam
Tóm tắt tiếng anh
From 1999 to 2004, Ho Chi Minh City (HCMC), Vie Nam reported 401 clinically suspected and 90 laboratory-confirmed diphtheria. To identify risk factors, a matched case-control study was conducted during 2005 and 2006. In total, 88 cases that occurred in 2003 and 2004 and 352 age- and sex-matched controls were studied. No DPT/DT immunisation (odds ratio, 9.9 [95% CI, 1.9-52.3]) and bathing only once a day or less (OR 1.7 [95% CI, 1.0-2.9]) were associated with diphtheria incidence. Estimated vaccine efficacy of three or more DPT/DT doses was 88%. Immunising children with zero-dose status of diphtheria toxoid inoculation, rather than the introduction of booster doses, and the promotion of skin hygiene were considered to be the priority interventions in controlling the endemic diphtheria in HCMC. � 2010 Elsevier Ltd.
