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Vectors and malaria transmission in deforested, rural communities in north-central Vietnam

Do Manh C. Entomology Department, Military Institute of Hygiene and Epidemiology, Hanoi, Viet Nam|
Cooper R.D. | Le Ngoc A. | Xuan T.N. | Van Nguyen D. | Lein C.T. Australian Army Malaria Institute, Gallipoli Barracks, Enoggera, QLD 4051, Australia| Le Quang T. Military Preventive Medicine Centre, Ho Chi Minh City, Viet Nam| Thi Van V.N. CSIRO Entomology, Long Pocket Laboratories, Indooroopilly, QLD 4068, Australia| Beebe N.W. School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia|

Malaria Journal Số 1, năm 2010 (Tập 9, trang -)

ISSN: 14752875

ISSN: 14752875

DOI: 10.1186/1475-2875-9-259

Tài liệu thuộc danh mục: Scopus



Từ khóa: circumsporozoite protein; circumsporozoite protein, Protozoan; protozoal protein; Anopheles; article; deforestation; disease carrier; disease transmission; ecology; enzyme linked immunosorbent assay; malaria; nonhuman; polymerase chain reaction; rural area; sequence analysis; species identification; Viet Nam; zoology; animal; Anopheles; buffalo; cattle; child; classification; disease transmission; DNA sequence; female; genetics; growth, development and aging; human; infant; newborn; parasitology; preschool child; rural population; season; Viet Nam; Animals; Anopheles; Buffaloes; Cattle; Child; Child, Preschool; Disease Vectors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Infant; Infant, Newborn; Malaria; Polymerase Chain Reaction; Protozoan Proteins; Rural Population; Seasons; Sequence Analysis, DNA; Vietnam
Tóm tắt tiếng anh
Background. Malaria is still prevalent in rural communities of central Vietnam even though, due to deforestation, the primary vector Anopheles dirus is uncommon. In these situations little is known about the secondary vectors which are responsible for maintaining transmission. Basic information on the identification of the species in these rural communities is required so that transmission parameters, such as ecology, behaviour and vectorial status can be assigned to the appropriate species. Methods. In two rural villages - Khe Ngang and Hang Chuon - in Truong Xuan Commune, Quang Binh Province, north central Vietnam, a series of longitudinal entomological surveys were conducted during the wet and dry seasons from 2003 - 2007. In these surveys anopheline mosquitoes were collected in human landing catches, paired human and animal bait collections, and from larval surveys. Specimens belonging to species complexes were identified by PCR and sequence analysis, incrimination of vectors was by detection of circumsporozoite protein using an enzyme-linked immunosorbent assay. Results. Over 80% of the anopheline fauna was made up of Anopheles sinensis, Anopheles aconitus, Anopheles harrisoni, Anopheles maculatus, Anopheles sawadwongporni, and Anopheles philippinensis. PCR and sequence analysis resolved identification issues in the Funestus Group, Maculatus Group, Hyrcanus Group and Dirus Complex. Most species were zoophilic and while all species could be collected biting humans significantly higher densities were attracted to cattle and buffalo. Anopheles dirus was the most anthropophilic species but was uncommon making up only 1.24% of all anophelines collected. Anopheles sinensis, An. aconitus, An. harrisoni, An. maculatus, An. sawadwongporni, Anopheles peditaeniatus and An. philippinensis were all found positive for circumsporozoite protein. Heterogeneity in oviposition site preference between species enabled vector densities to be high in both the wet and dry seasons allowing for year round transmission. Conclusions. In rural communities in north central Vietnam, malaria transmission was maintained by a number of anopheline species which though collected feeding on humans were predominantly zoophilic, this behaviour allows for low level but persistent malaria transmission. The important animal baits - cattle and buffalo - were kept in the village and barrier spraying around these animals may be more effective at reducing vector densities and longevity than the currently used indoor residual spraying. � 2010 Do Manh et al; licensee BioMed Central Ltd.

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